The PK/PD Integration and Resistance of Tilmicosin against Mycoplasma hyopneumoniae
نویسندگان
چکیده
منابع مشابه
Diagnosis of Mycoplasma hyopneumoniae.
Mycoplasma hyopneumoniae, the cause of enzootic pneumonia, remains an important pathogen in the swine industry. This small, complex organism colonizes the ciliated cells of the respiratory tract, resulting in little exposure to the immune system. Confirming the presence of M. hyopneumoniae, as well as identifying its role in respiratory disease and pneumonia, remains challenging to the veterina...
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Methods: Isolates were cultured directly from porcine lung sections and positively identified as M. hyopneumoniae using an indirect-fluorescent antibody (IFA) method. A Sensititre® plate broth microdilution technique was used to determine the minimum inhibitory concentrations (MICs) of each of the antimicrobials. Inocula concentrations were determined by serial tenfold dilutions of the 14 M. hy...
متن کاملMycoplasma Hyopneumoniae - Epidemiology and Control
Respiratory disease is an economically devastating syndrome affecting swine production worldwide. Mycoplasma hyopneumoniae (M. hyo) is a key pathogen involved with enzootic pneumonia (EP) and the Porcine Respiratory Disease Complex (PRDC). Enzootic pneumonia is composed of M. hyo and secondary bacteria such as Pasteurella multocida, Streptococcus suis, Haemophilus parasuis, and Actinobacillus p...
متن کاملGenes involved in translation of Mycoplasma hyopneumoniae and Mycoplasma synoviae
This is a report on the analysis of genes involved in translation of the complete genomes of Mycoplasma hyopneumoniae strain J and 7448 and Mycoplasma synoviae. In both genomes 31 ORFs encoding large ribosomal subunit proteins and 19 ORFs encoding small ribosomal subunit proteins were found. Ten ribosomal protein gene clusters encoding 42 ribosomal proteins were found in M. synoviae, while 8 cl...
متن کاملIntradermal vaccination for Mycoplasma hyopneumoniae
Results: Injection site reactions were minimal for all vaccines. Pigs vaccinated ID, either by needle or needleless injector, had significantly higher M hyopneumoniae antibody titers than did pigs vaccinated by IM injection. Pigs vaccinated by needleless ID injection had lower lung lesion scores and higher IgA and IgG titers in bronchoalveolar lavage fluid than did nonvaccinates following chall...
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ژورنال
عنوان ژورنال: Pathogens
سال: 2020
ISSN: 2076-0817
DOI: 10.3390/pathogens9060487